As an owner of a 2015 TLX V-6 I can say that it handles pretty good but not great. I prefered the handling of my '08 TL Type S much better and wish that Acura could have incorporated some more of that handling into the TLX. It's not the canyon burner the ads would have you believe but gets the job done.
I had driven both the V-6 and I-4 and really like the V-6. It just gets up and goes when you put your foot into it. I suggest that you take both the V-6 and I-4 for an extended test ride on various roads. Not a 10 minute ride with the sales person and make up your mind which you prefer.
I've had "issues" with the 9 speed trans and a couple of other problems which are documented in this forum. Guess I got the short straw on this car as my 3 other Acura's were "bullet proof".