I have a 2005 with 186k and the only repair I have ever done is a new radiator. I am thorough with all scheduled maintenance, so you would want to check that it has been done, like any car.
Two questions that I think of: 1. has the timing belt been changed? If not, it needs to be and that is a $700 negotiation item. 2. Has the transmission fluid been changed? On older pilots this was a problem area.
It has been a great car for our family, among the very best value of any cars I have owned.