zcd1, I agree, bias towards an automaker should not be allowed on this website because it misleads the original poster. He constantly posts GM and it's annoying. This website might as well be called buyaGM.com.
Back to the OP: The RDX perfectly fits your top three priorities, but it is aging and outdated. The RDX is recommended premium, but can take regular gas. I wouldn't risk the engine damage running regular in a premium gas-recommended engine. I wouldn't consider the RDX as a luxury car, but it's priced like one. The interior is inexcusably bad for a luxury SUV and it doesn't handle as well as it should. The RDX used to be a good luxury SUV, but others have far surpassed it. It, however, is one of the only cars that fit your specifications and it's reliable. It has many knobs and buttons in the dash.
The 2016-2017 Lincoln MKX drives better than the RDX in handling, acceleration, quietness, and luxury, but the reliability is not good. The throttle body is notorious for killing the car in its tracks. Many reports of stopping in the middle of the freeway and almost getting killed. They haven't recalled it yet. Typical Ford. The interior controls are easier to use IMO in the MKX than the old RDX. However, there are only two knobs in the Lincoln. Between the Acura and Lincoln, I'd take the Acura for the reliability and brand rep, but honestly I'd never buy either. If you decide on the MKX, look at the Ford Edge because it's the same car basically but cheaper.
The 2017 GMC Terrain is an option, but it's really dated. It looks like a car from 2010 inside and out. It does have the V6 though. Several reviewers have said even the V6 300+hp is not a lot of power for this SUV.
You might like the Hyundai Santa Fe Sport. It is available with a naturally aspirated 4 cylinder or a 2.0T 4 cylinder. The 4 cylinder is actually just as fast as the turbo four. Has a great CPO program like Lexus except that the only warranty is the one that comes with the car from when new (10 years/100,000 miles). Has a good infotainment system that's easy to use. Also, the Kia Sorento is a great SUV. Available with a V6 (and turbo 4) and no CVT, comfortable, easy controls, same warranty as the Hyundai, and nice to drive. I would recommend the Nissan Murano if it didn't have an unreliable CVT.
Probably the best choice is the Lexus RX. Smooth, comfortable, not really techy inside for the previous generation (2010-2015), reliable, luxurious, and has an NA V6. #1 selling luxury car/SUV in America. Might have to go a little older than 2015, but it has a tried and true powertrain. You have a very low chance of having an issue with it. Lexus' CPO warranty is 2 years/unlimited mileage after the 4 year basic new car warranty, so you get up to 6 years/ unlimited miles. Also, they cover dealer maintenance and roadside assistance for 2 years/20,000 miles. Interesting thing I read: If your vehicle has mechanical difficulty while you're away from home, you will be reimbursed for meals and lodging for a maximum of three nights (up to $200 per night) while repairs are performed on your car, in addition to reimbursement for a rental car for up to five days (up to $50 per day). So Lexus has a sweet CPO program.
Pretty much anything will be better than your Wrangler no offense. All these cars are at least OK, but there are definitely some that are better than others like I pointed out. Good luck and tell us what you buy! :)