If your budget is $10k then I don't think there is much out there that matches your description. If the car is mostly highway driving does it need to be fun to drive or quiet? Those are usually two ends of the spectrum. I would say quietness is more important so I would just get a Prius and it would fit all of your needs except for the fun to drive part. It is decently quiet, specifically compared to an older Civic or Mazda3 which I recommend also.
If your budget is $100k like you stated then I think a Lexus, Genesis, or Tesla would be the best bet because of reliability. Lexus ES (comes in a hybrid also) is too close in comfort to an LS now to justify the LS' huge price increase. A Genesis G90 is super comfortable and quiet and there are many reasons to go with the Tesla although they are not the most luxurious.