I prefer the styling and handling of the Accord, and its conventional transmission. Nissan has tuned its CVTs to feel more and more like conventional transmissions in casual driving, but in aggressive driving they still sound and feel like CVT-based drivetrains.
I'd personally prefer the Accord with a manual transmission.
The main advantage of the Nissan is that it is somewhat more upscale and distinctive. How attractive it is depends heavily on your personal taste.
I'd expect the Honda to be more reliable in the long run. Up to 100,000 or even 120,000 miles I'd expect few problems from either.