The third row and luggage space behind that row in a crossover are much tighter than in a minivan. So, if you aren't averse to buying another minivan, that's the way to go.
The Sienna and Odyssey are more reliable for a given model year, while you can get a newer Chrysler or Dodge for the same amount of money, so reliability can be a bit of a wash. But the last isn't as likely to go 225k miles.
The Sienna is the only one available with AWD, if this is a consideration. And the Sienna probably has the best chance of making it to 225k.