I can think of three cars that fit your parameters-
2008-2010 Lexus IS 250/350- great drive, rock-solid reliable, but very tight on interior space (especially back seat), based on interior space it actually falls into the subcompact category.
2008-2011 Acura TSX- 2008 was the final year for the first generation but it is still a fantastic car; the 2009-newer are slightly larger and more refined and starting in 2010, you could choose between the standard 2.4L I-4 and 3.5L V6 (201hp vs. 280hp). If rear seat room legroom is important, this is a substantial increase compared to the Lexus IS (about 4in more).
2008 Acura TL- the final year of the second generation TL (2004-2008) and the final year before they put the 'beak' on the front; all of the TSX virtues apply and it has a standard 258hp 3.2L V6; it is also the most refined and smooth riding/driving of these three cars.