I think a Toyota Matrix would be the most reliable and give you some cargo room. I wouldn't be suprised to find that a Prius has more cargo room than a Matrix. It is amazing to see what people can fit in the trunk of a Prius and you'll be saving gas. Some other choices would be the Honda CR-V and Toyota RAV4. If you need something bigger then the Toyota Highlander would be the most reliable. I'm just going based off your need for reliability and space because you didn't mention any other preferences.